IL10RB Antibody

Size

100ug

Clone Number

Aliases

Cd210 antibody; CDw210b antibody; CRF2 4 antibody; CRF2-4 antibody; CRFB4 antibody; Cytokine receptor class II antibody; Cytokine receptor class II CRF2 4 antibody; Cytokine receptor class-II member 4 antibody; Cytokine receptor family 2 member 4 antibody; Cytokine receptor family II member 4 antibody; D21S58 antibody; D21S66 antibody; I10R2_HUMAN antibody; IL-10 receptor subunit beta antibody; IL-10R subunit 2 antibody; IL-10R subunit beta antibody; IL-10R2 antibody; IL-10RB antibody; IL10R2 antibody; IL10RB antibody; Interleukin 10 receptor beta antibody; Interleukin-10 receptor subunit 2 antibody; Interleukin-10 receptor subunit beta antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q08334

Immunogen

Recombinant Human Interleukin-10 receptor subunit beta protein (79-219AA)

Raised in

Rabbit

Species Reactivity

Human, Rat

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:50-1:200

Background

Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

IL10RB

Research Areas

Immunology; Signal transduction