IL-9R(Phospho Ser519) Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human IL-9R around the phosphorylation site of Ser519. AA range:472-521

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

57147

synonyms

Interleukin-9 receptor; IL9R; Interleukin-9 receptor; IL-9 receptor; IL-9R; CD antigen CD129