IL-2 Polyclonal Antibody

Ab type

Primary antibody

Background

Interleukin-2 encoded by IL2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.

Reactivity

Human;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human IL-2. AA range:16-65

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

17628

synonyms

IL2; IL 2; IL 2; Interleukin-2; IL-2; T-cell growth factor; TCGF; Aldesleukin