IL-1Beta Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by IL1A is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human IL-1beta. AA range:113-162

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

30607

synonyms

IL1B; IL1F2; Interleukin-1 beta; IL-1 beta; Catabolin