IKKGamma Polyclonal Antibody

Ab type

Primary antibody

Background

IKBKG (inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma) encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in IKBKG result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to IKBKG is located in an adjacent region of the X chromosome.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthetic peptide from human protein at AA range: 60-120

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

48198

synonyms

NF-kappa-B essential modulator (NEMO) (FIP-3) (IkB kinase-associated protein 1) (IKKAP1) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (I-kappa-B kinase subunit gamma) (IKK-gamma) (IKKG)