IGFBP3 Polyclonal Antibody

Ab type

Primary antibody

Background

IGFBP3 is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes Insulin-like growth factor-binding protein 3 with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human IGFBP-3. AA range:151-200

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

31674

synonyms

IGFBP3; IBP3; Insulin-like growth factor-binding protein 3; IBP-3; IGF-binding protein 3; IGFBP-3