IFNAR2 Antibody

Size

100ul

Clone Number

Aliases

Human interferon alpha/beta receptor antibody; IFN alpha REC antibody; IFN R antibody; IFN-a/?R2 antibody; IFN-a/?R? antibody; IFN-alpha binding protein antibody; IFN-alpha/beta receptor 2 antibody; IFN-R-2 antibody; IFNABR antibody; IFNAR2 antibody; IFNARB antibody; IFNR antibody; INAR2_HUMAN antibody; Interferon (alpha beta and omega) receptor 2 antibody; Interferon alpha binding protein antibody; Interferon alpha/beta receptor 2 antibody; Interferon alpha/beta receptor beta chain antibody; Type I interferon receptor 2 antibody; Type I interferon receptor antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P48551

Immunogen

Recombinant Human Interferon alpha/beta receptor 2 protein (27-243AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:500-1:1000, IHC:1:20-1:200

Background

Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 is a potent inhibitor of type I IFN receptor activity.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

IFNAR2

Research Areas

Epigenetics and Nuclear Signaling; Cancer; Immunology; Signal transduction