IF122 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD)| which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes| including cell cycle progression| signal transduction| apoptosis| and gene regulation. This cytoplasmic protein contains seven WD repeats and an AF-2 domain which function by recruiting coregulatory molecules and in transcriptional activation. Mutations in this gene cause cranioectodermal dysplasia-1. A related pseudogene is located on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human IF122

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

136510

synonyms

IF122