IDE Antibody

Size

100ug

Clone Number

Aliases

Abeta-degrading protease antibody; FLJ35968 antibody; Ide antibody; IDE_HUMAN antibody; Insulin protease antibody; Insulin-degrading enzyme antibody; Insulinase antibody; Insulysin antibody; OTTHUMP00000020097 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P14735

Immunogen

Recombinant Human Insulin-degrading enzyme protein (501-800AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

IDE

Research Areas

Neuroscience; Cancer; Cardiovascular; Cell biology; Metabolism; Signal transduction