ID3 Antibody

Size

100ug

Clone Number

Aliases

1R21 antibody; bHLHb25 antibody; Class B basic helix-loop-helix protein 25 antibody; DNA binding protein inhibitor ID 3 antibody; DNA-binding protein inhibitor ID-3 antibody; HEIR 1 antibody; HEIR1 antibody; Helix loop helix protein HEIR 1 antibody; Helix loop helix protein HEIR1 antibody; Helix-loop-helix protein HEIR-1 antibody; HLH642 antibody; ID 3 antibody; ID like protein inhibitor HLH 1R21 antibody; ID like protein inhibitor HLH 462 antibody; ID-like protein inhibitor HLH 1R21 antibody; ID3 antibody; ID3_HUMAN antibody; Inhibitor of DNA binding 3 antibody; Inhibitor of DNA binding 3 dominant negative helix loop helix protein antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q02535

Immunogen

Recombinant Human DNA-binding protein inhibitor ID-3 protein (27-99AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IF; Recommended dilution: IF:1:50-1:200

Background

Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Involved in myogenesis by inhibiting skeletal muscle and cardiac myocyte differentiation and promoting muscle precursor cells proliferation. Inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ID3

Research Areas

Epigenetics and Nuclear Signaling; Cancer; Cell biology; Immunology; Stem cells