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ABCbiolab

SKU:ABCCS00800

ICAM1 Monoclonal Antibody

ICAM1 Monoclonal Antibody

Regular price $384.00 USD
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Size

Clone Number

Aliases

BB 2; BB2; CD 54; CD_antigen=CD54; CD54; Cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM 1; ICAM-1; ICAM1; ICAM1_HUMAN; Intercellular adhesion molecule 1; Major group rhinovirus receptor; MALA 2; MALA2; MyD 10; MyD10; P3.58

Immunogen Species

Human

UniProt ID

P05362

Immunogen

Purified recombinant human ICAM1(C-terminus) protein fragments expressed in E.coli.

Raised in

Mouse

Species Reactivity

Human

Tested Applications

ELISA,WB,ICC;Recommended dilution:WB:1:500-1:5000,ICC:1:50-1:200

Background

ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

Clonality

Monoclonal

Isotype

IgG2b

Purification Method

Affinity purified

Conjugate

Non-conjugated

Buffer

Purified mouse monoclonal in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.

Form

liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ICAM1

Research Areas

Cardiovascular;Immunology;Stem cells

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