ABCbiolab
SKU:ABCB13066
IκB-beta(Phospho Thr19) Polyclonal Antibody
IκB-beta(Phospho Thr19) Polyclonal Antibody
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Ab type
Primary antibody
Background
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Immunogen
The antiserum was produced against synthesized peptide derived from human IkappaB-beta around the phosphorylation site of Thr19. AA range:4-53
Storage Stability
-20°C for 1 year
Concentration
1 mg/ml
MolecularWeight_Da
37771
synonyms
NF-kappa-B inhibitor beta; NFKBIB; IKBB; TRIP9; NF-kappa-B inhibitor beta; NF-kappa-BIB; I-kappa-B-beta; IkB-B; IkB-beta; IkappaBbeta; Thyroid receptor-interacting protein 9; TR-interacting protein 9; TRIP-9
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