Dima Biotech

SKU:FLP120825

Human P2RX3-Strep full length protein-synthetic nanodisc

Human P2RX3-Strep full length protein-synthetic nanodisc

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Tag

C-Flag&Strep Tag

Target

Synonyms

P2X3

Description

Human P2RX3-Strep full length protein-synthetic nanodisc

Delivery

6~8weeks

Uniprot ID

P56373

Expression Host

HEK293

Protein Families

Ion Channels: ATP Receptors

Protein Pathways

N/A

Molecular Weight

The human full length P2RX3-Strep protein has a MW of 44.3 kDa

Formulation & Reconstitution

Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage & Shipping

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Background

This gene encodes a member of the P2X purinergic receptor (purinoceptor) gene family which includes seven members (P2RX1 – P2RX7). P2X purinoceptors are a family of cation-permeable, ligand-gated ion channels that open in response to the binding of extracellular adenosine 5'-triphosphate (ATP). The encoded protein is a subunit of the trimeric P2X3 receptor ion channel which is expressed by sensory or autonomic neurons. A deficiency of the orthologous protein in mice is associated with reduced pain-related behavior and urinary bladder hyporeflexia. [provided by RefSeq, Aug 2017]

Usage

Research use only

Conjugate

Unconjugated

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