1 1

Dima Biotech

FLP100095

Human ACKR3 full length protein-synthetic nanodisc

Human ACKR3 full length protein-synthetic nanodisc

$4,400.00 USD
$4,400.00 USD
Sale Sold out
Shipping calculated at checkout.
Size
PRODUCT DATA
TARGET

SYNONYMS

ACKR3; CMKOR1; CXC-R7; CXCR-7; GPR159; RDC-1; RDC1
DESCRIPTION

Human CXCR7 full length protein-synthetic nanodisc
DELIVERY

In Stock
UNIPROT ID

P25106
EXPRESSION HOST

HEK293
PROTEIN FAMILIES

Druggable Genome, GPCR, Transmembrane
PROTEIN PATHWAYS

——
MOLECULAR WEIGHT

The human full length CXCR7 protein has a MW of 41.5 kDa
FORMULATION & RECONSTITUTION

Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
BACKGROUND

A member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.
USAGE

Research use only
IMAGES

elisa-FLP100095 CXCR7 Fig.1 Elisa 1
Figure1. Elisa plates were pre-coated with Flag Tag CXCR7-Nanodisc (0.2μg/per well). Serial diluted anti-CXCR7 monoclonal antibody (DMC100443) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-CXCR7 monoclonal antibody binding with CXCR7-Nanodisc is 14.28ng/ml.
page-FLP100095 CXCR7 Fig.2 SDS PAGE 1
Figure2. Human CXCR7-Nanodisc, Flag Tag on SDS-PAGE

View full details