HTRA2 Antibody

Size

100ul

Clone Number

Aliases

High temperature requirement protein A2 antibody; HTRA 2 antibody; HtrA like serine protease antibody; HtrA serine peptidase 2 antibody; HtrA; E. coli; homolog of; 2 antibody; HtrA2 antibody; HTRA2_HUMAN antibody; mitochondrial antibody; Omi stress regulated endoprotease antibody; Omi stress-regulated endoprotease antibody; PARK 13 antibody; PARK13 antibody; Protease serine 25 antibody; PRSS 25 antibody; PRSS25 antibody; Serine protease 25 antibody; Serine protease HTRA2 antibody; Serine protease HTRA2 mitochondrial antibody; Serine protease htra2 mitochondrial precursor antibody; Serine protease omi antibody; Serine proteinase OMI antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O43464

Immunogen

Recombinant Human Serine protease HTRA2, mitochondrial protein (334-458AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200

Background

Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

HTRA2

Research Areas

Neuroscience; Cancer; Cell biology; Metabolism