HTR1A Antibody, HRP conjugated

Size

100ug

Clone Number

Aliases

5 HT 1A antibody; 5 HT receptor 1A antibody; 5 HT1A antibody; 5 HT1A receptor antibody; 5 hydroxytryptamine (serotonin) receptor 1A antibody; 5 hydroxytryptamine (serotonin) receptor 1A G protein coupled antibody; 5 hydroxytryptamine receptor 1A antibody; 5-HT-1A antibody; 5-HT1A antibody; 5-hydroxytryptamine receptor 1A antibody; 5HT 1A antibody; 5HT 1A receptor antibody; 5HT receptor 1A antibody; 5HT1a antibody; 5HT1A_HUMAN antibody; ADRB2RL1 antibody; ADRBRL1 antibody; G 21 antibody; G protein coupled receptor antibody; G-21 antibody; Gpcr 18 antibody; Gpcr18 antibody; Guanine nucleotide binding regulatory protein-coupled receptor antibody; Htr1a antibody; PFMCD antibody; Serotonin 1A receptor antibody; Serotonin 5HT1A receptor antibody; Serotonin receptor 1A antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P08908

Immunogen

Recombinant Human 5-hydroxytryptamine receptor 1A protein (230-334AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

HRP

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

HTR1A

Research Areas

Neuroscience; Cancer; Metabolism; Signal transduction