HSD3B1 Antibody

Size

100ug

Clone Number

Aliases

3 beta and steroid delta isomerase 1 antibody; 3 beta and steroid hydroxy delta 5 steroid dehydrogenase antibody; 3 beta HSD I antibody; 3 beta-hydroxysteroid dehydrogenase/Delta 5--&gt,4-isomerase type I antibody; 3-beta-HSD I antibody; 3-beta-hydroxy-5-ene steroid dehydrogenase antibody; 3BETAHSD antibody; 3BH antibody; 3BHS1_HUMAN antibody; 3BHSD antibody; Delta-5-3-ketosteroid isomerase antibody; HGNC:5217 antibody; HSD3B antibody; HSD3B1 antibody; HSDB3 antibody; HSDB3A antibody; Hydroxy delta 5 steroid dehydrogenase 3 beta and steroid delta isomerase 1 antibody; Hydroxy delta 5 steroid dehydrogenase antibody; Progesterone reductase antibody; SDR11E1 antibody; Steroid Delta-isomerase antibody; trophoblast antigen antibody; Trophoblast antigen FDO161G antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P14060

Immunogen

Recombinant Human 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 protein (127-267AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200

Background

3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. Efficiently catalyzes the transformation of pregnenolone to progesterone, 17-alpha-hydroxypregnenolone to 17-alpha-hydroxyprogesterone, DHEA to 4-androstenedione, dihydrotestosterone to 5-alpha-androstane-3 beta,17 beta-diol, dehydroepiandrosterone to androstenedione and 5-alpha-androstan-3 beta,17 beta-diol to 5-alpha-dihydrotestosterone.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

HSD3B1

Research Areas

Cancer; Metabolism; Signal transduction