HPN Antibody

Size

100ug

Clone Number

Aliases

EC 3.4.21. antibody; HEPS antibody; HEPS_HUMAN antibody; Hepsin antibody; Hpn antibody; Serine protease hepsin antibody; Serine protease hepsin catalytic chain antibody; Serine protease hepsin non catalytic chain antibody; TMPRSS 1 antibody; TMPRSS1 antibody; Transmembrane protease serine 1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P05981

Immunogen

Recombinant Human Serine protease hepsin protein (294-413AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse, Rat

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200

Background

Serine protease that cleaves extracellular substrates, and contributes to the proteolytic processing of growth factors, such as HGF and MST1/HGFL (PubMed:21875933, PubMed:15839837). Plays a role in cell growth and maintenance of cell morphology (PubMed:8346233, PubMed:21875933). Plays a role in the proteolytic processing of ACE2 (PubMed:24227843). Mediates the proteolytic cleavage of urinary UMOD that is required for UMOD polymerization (PubMed:26673890).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

HPN

Research Areas

Cancer; Cell biology