HoxD3 Polyclonal Antibody

Ab type

Primary antibody

Background

HOXD3 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. Homeobox protein Hox-D3 encoded by this gene may play a role in the regulation of cell adhesion processes.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human HOXD3. AA range:211-260

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

45730

synonyms

HOXD3; HOX1D; HOX4A; Homeobox protein Hox-D3; Homeobox protein Hox-4A