HoxA5 Polyclonal Antibody

Ab type

Primary antibody

Background

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA5 is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from the N-terminal region of human HoxA5.

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

29345

synonyms

HOXA5; HOX1C; Homeobox protein Hox-A5; Homeobox protein Hox-1C