HoxA11/D11 Polyclonal Antibody

Ab type

Primary antibody

Background

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA11 is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. HOXA11 is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human HOXA11/D11. AA range:216-265

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

34486

synonyms

HOXA11; HOX1I; Homeobox protein Hox-A11; Homeobox protein Hox-1I; HOXD11; HOX4F; Homeobox protein Hox-D11; Homeobox protein Hox-4F