HOMER2 Antibody, HRP conjugated

Size

100ug

Clone Number

Aliases

HOMER2 antibody; Homer protein homolog 2 antibody; Homer-2 antibody; Cupidin antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9NSB8

Immunogen

Recombinant Human Homer protein homolog 2 protein (1-343AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

HRP

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

HOMER2

Research Areas

Epigenetics and Nuclear Signaling; Neuroscience; Signal transduction