HLTF Antibody

Size

100ug

Clone Number

Aliases

DNA-binding protein/plasminogen activator inhibitor 1 regulator antibody; Helicase like transcription factor antibody; Helicase-like transcription factor antibody; HIP116 antibody; HIP116A antibody; HLTF 1 antibody; Hltf antibody; HLTF_HUMAN antibody; HLTF1 antibody; p113 antibody; RING finger protein 80 antibody; RNF80 antibody; SMARC A3 antibody; SMARCA 3 antibody; SMARCA3 antibody; SNF2-like 3 antibody; SNF2L3 antibody; Sucrose nonfermenting protein 2 like 3 antibody; Sucrose nonfermenting protein 2-like 3 antibody; SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 3 antibody; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a3 antibody; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 antibody; ZBU 1 antibody; ZBU1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q14527

Immunogen

Recombinant Human Helicase-like transcription factor protein (332-476AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC, IP; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IP:1:200-1:2000

Background

Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for \\\'Lys-63\\\'-linked polyubiquitination of chromatin-bound PCNA.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

HLTF

Research Areas

Epigenetics and Nuclear Signaling; Cancer; Cell biology