Histone H2B type 1-K Antibody

Size

100ul

Clone Number

4G10

Aliases

Histone H2B type 1-K, H2B K, HIRA-interacting protein 1, HIST1H2BK, H2BFT, HIRIP1

Immunogen Species

Human

UniProt ID

O60814

Immunogen

A synthesized peptide

Raised in

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:5000-1:10000, IHC:1:50-1:500

Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Clonality

Monoclonal

Isotype

Rabbit IgG

Purification Method

Affinity-chromatography

Conjugate

Non-conjugated

Buffer

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

HIST1H2BK

Research Areas

Epigenetics and Nuclear Signaling