Histone H2B Polyclonal Antibody

Ab type

Primary antibody

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. HIST1H2BA is intronless and encodes a replication-dependent histone that is a testis/sperm-specific member of the histone H2B family. Transcripts from HIST1H2BA contain a palindromic termination element.

Reactivity

Human;Mouse;Monkey

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human Histone H2B. AA range:10-59

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

14167/13950/13906

synonyms

H2BFS; Histone H2B type F-S; Histone H2B.s; H2B/s