Histone H2B(Phospho-Ser14) Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A| H2B| H3| and H4) form an octamer| around which approximately 146 bp of DNA is wrapped in repeating units| called nucleosomes. The linker histone| H1| interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized phosho peptide around human Histone H2B (Ser14)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

Histone H2B ;Ser14 ; Histone H2B type 1-H; Histone H2B.j; H2B/j