Histone H2A Polyclonal Antibody

Ab type

Primary antibody

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. HIST1H2AI (histone cluster 1 H2A family member i) is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from HIST1H2AI lack polyA tails but instead contain a palindromic termination element. HIST1H2AI is found in the small histone gene cluster on chromosome 6p22-p21.3.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human Histone H2A.

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

14091

synonyms

HIST1H2AG; H2AFP; HIST1H2AI; H2AFC; HIST1H2AK; H2AFD; HIST1H2AL; H2AFI; HIST1H2AM; H2AFN; Histone H2A type 1; H2A.1; Histone H2A/p