Histamine H2 Receptor Polyclonal Antibody

Ab type

Primary antibody

Background

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for HRH2.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human HRH2. AA range:131-180

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

40098

synonyms

HRH2; Histamine H2 receptor; H2R; HH2R; Gastric receptor I