ABCbiolab
SKU:ABCCS47812
HIST2H3A Antibody
HIST2H3A Antibody
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Size
100ug
Clone Number
Aliases
HIST2H3A; antibody; HIST2H3C antibody; H3F2 antibody; H3FM; antibody; HIST2H3D antibody; Histone H3.2 antibody; Histone H3/m antibody; Histone H3/o antibody
Immunogen Species
Homo sapiens (Human)
UniProt ID
Q71DI3
Immunogen
Recombinant Human Histone H3.2 protein (108-136AA)
Raised in
Rabbit
Species Reactivity
Human, Mouse
Tested Applications
ELISA, WB, IHC, IF; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Conjugate
Non-conjugated
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Stroage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names
HIST2H3A
Research Areas
Epigenetics and Nuclear Signaling
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