HIST2H2BE Antibody

Size

100ul

Clone Number

Aliases

HIST2H2BE antibody; H2BFQHistone H2B type 2-E antibody; Histone H2B-GL105 antibody; Histone H2B.q antibody; H2B/q antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q16778

Immunogen

Recombinant Human Histone H2B type 2-E protein (2-126AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

HIST2H2BE

Research Areas

Epigenetics and Nuclear Signaling