HIST1H2BD Antibody

Size

100ug

Clone Number

Aliases

HIST1H2BD antibody; H2BFB antibody; HIRIP2 antibody; Histone H2B type 1-D antibody; HIRA-interacting protein 2 antibody; Histone H2B.1 B antibody; Histone H2B.b antibody; H2B/b antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P58876

Immunogen

Recombinant Human Histone H2B type 1-D protein (2-57AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

HIST1H2BD

Research Areas

Epigenetics and Nuclear Signaling