HIST1H2AC Antibody

Size

100ul

Clone Number

Aliases

HIST1H2AC antibody; H2AFL antibody; Histone H2A type 1-C antibody; Histone H2A/l antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q93077

Immunogen

Recombinant Human Histone H2A type 1-C protein (2-130AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200

Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

HIST1H2AC

Research Areas

Epigenetics and Nuclear Signaling