HGF Polyclonal Antibody

Ab type

Primary antibody

Background

HGF (hepatocyte growth factor) encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in HGF are associated with nonsyndromic hearing loss.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human HGF. AA range:500-600

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

83134

synonyms

HGF; HPTA; Hepatocyte growth factor; Hepatopoietin-A; Scatter factor; SF