ABCbiolab
SKU:ABCCS62560
HECTD3 Antibody
HECTD3 Antibody
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Size
100ug
Clone Number
Aliases
E3 ubiquitin-protein ligase HECTD3 antibody; HECD3_HUMAN antibody; HECT antibody; HECT domain containing protein 3 antibody; HECT domain-containing protein 3 antibody; HECTD3 antibody; Probable E3 ubiquitin protein ligase HECTD3 antibody
Immunogen Species
Homo sapiens (Human)
UniProt ID
Q5T447
Immunogen
Recombinant Human E3 ubiquitin-protein ligase HECTD3 protein (682-785AA)
Raised in
Rabbit
Species Reactivity
Human
Tested Applications
ELISA, IF; Recommended dilution: IF:1:20-1:200
Background
E3 ubiquitin ligases accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of TRIOBP and its subsequent proteasomal degradation, thus faciliting cell cycle progression by regulating the turn-over of TRIOBP. Mediates also ubiquitination of STX8 (By similarity).
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Conjugate
Non-conjugated
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Stroage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names
HECTD3
Research Areas
Cell biology
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