HDAC7 Polyclonal Antibody

Ab type

Primary antibody

Background

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 7 encoded by HDAC7 has sequence homology to members of the histone deacetylase family. HDAC7 is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for HDAC7.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human HDAC7A. AA range:121-170

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

102927

synonyms

HDAC7; HDAC7A; Histone deacetylase 7; HD7; Histone deacetylase 7A; HD7a