HDAC6(Phospho Ser22) Polyclonal Antibody

Ab type

Primary antibody

Background

Histones play a critical role in transcriptional regulation| cell cycle progression| and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human HDAC6 around the phosphorylation site of Ser22. AA range:7-56

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

131431

synonyms

Histone deacetylase 6; HDAC6; KIAA0901; JM21; Histone deacetylase 6; HD6