HDAC4(Phospho Ser632) Polyclonal Antibody

Ab type

Primary antibody

Background

Histones play a critical role in transcriptional regulation| cell cycle progression| and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly| but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human HDAC4 around the phosphorylation site of Ser632. AA range:598-647

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

119070

synonyms

Histone deacetylase 4; HDAC4; KIAA0288; Histone deacetylase 4; HD4