Hck Polyclonal Antibody

Ab type

Primary antibody

Background

Tyrosine-protein kinase HCK encoded by HCK is a member of the Src family of tyrosine kinases. Tyrosine-protein kinase HCK is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human HCK. AA range:381-430

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

59600

synonyms

HCK; Tyrosine-protein kinase HCK; Hematopoietic cell kinase; Hemopoietic cell kinase; p59-HCK/p60-HCK; p59Hck; p61Hck