HBP1(Phospho Ser402) Polyclonal Antibody

Ab type

Primary antibody

Background

Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.,Contains 1 AXH domain.,Contains 1 HMG box DNA-binding domain.,subunit:Binds the second PAH repeat of SIN3A (By similarity). Binds TCF4 and RB1.,

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human HBP1 around the phosphorylation site of Ser402. AA range:371-420

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

57645

synonyms

HMG box-containing protein 1; HBP1; HMG box-containing protein 1; HMG box transcription factor 1; High mobility group box transcription factor 1