HAT1 Antibody

Size

100ul

Clone Number

Aliases

HAT 1 antibody; hat1 antibody; HAT1_HUMAN antibody; Histidine aminotransferase 1 antibody; Histone acetyltransferase 1 antibody; Histone acetyltransferase 1 antibody; Histone acetyltransferase type B catalytic subunit antibody; KAT1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O14929

Immunogen

Recombinant Human Histone acetyltransferase type B catalytic subunit protein (245-419AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200

Background

Acetylates soluble but not nucleosomal histone H4 at \\\'Lys-5\\\' (H4K5ac) and \\\'Lys-12\\\' (H4K12ac) and, to a lesser extent, acetylates histone H2A at \\\'Lys-5\\\' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

HAT1

Research Areas

Epigenetics and Nuclear Signaling