HAS2 Antibody, Biotin conjugated

Size

100ug

Clone Number

Aliases

HA synthase 2 antibody; has2 antibody; HAS2_HUMAN antibody; Hyaluronan synthase 2 antibody; Hyaluronate synthase 2 antibody; Hyaluronic acid synthase 2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q92819

Immunogen

Recombinant Human Hyaluronan synthase 2 protein (70-359AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction and it is particularly responsible for the synthesis of high molecular mass hyaluronan. Required for the transition of endocardial cushion cells into mesenchymal cells, a process crucial for heart development. May also play a role in vasculogenesis. High molecular mass hyaluronan also play a role in early contact inhibition a process which stops cell growth when cells come into contact with each other or the extracellular matrix (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

HAS2

Research Areas

Neuroscience; Cardiovascular; Developmental biology; Signal transduction; Stem cells