H2AFY2 Antibody, Biotin conjugated

Size

100ug

Clone Number

Aliases

Core histone macro H2A2.2 antibody; Core histone macro-H2A.2 antibody; Core histone macroH2A2.2 antibody; H2A histone family member Y2 antibody; H2AFY2 antibody; H2AW_HUMAN antibody; Histone macroH2A2 antibody; Macro H2A.2 antibody; Macro H2A2 antibody; MacroH2A.2 antibody; MacroH2A2 antibody; mH2A2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9P0M6

Immunogen

Recombinant Human Core histone macro-H2A.2 protein (1-260AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

H2AFY2

Research Areas

Epigenetics and Nuclear Signaling