H11 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A| H2B| H3| and H4) form an octamer| around which approximately 146 bp of DNA is wrapped in repeating units| called nucleosomes. The linker histone| H1| interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human H11

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

23650

synonyms

H11