GZMM Antibody

Size

100ug

Clone Number

Aliases

GRAM_HUMAN antibody; Granzyme M (lymphocyte met ase 1) antibody; Granzyme M antibody; GranzymeM antibody; GZM M antibody; Gzmm antibody; HU Met 1 antibody; HU-Met-1 antibody; LMET 1 antibody; LMET1 antibody; Lymphocyte met ase 1 antibody; MET 1 antibody; Met 1 serine protease antibody; Met ase antibody; Met-1 serine protease antibody; Met-ase antibody; MET1 antibody; Met1 serine protease antibody; Natural killer cell granular protease antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P51124

Immunogen

Recombinant Human Granzyme M protein (98-243AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

GZMM

Research Areas

Cell biology