GSPT1 Antibody

Size

100ug

Clone Number

Aliases

GSPT1 antibody; ERF3AEukaryotic peptide chain release factor GTP-binding subunit ERF3A antibody; Eukaryotic peptide chain release factor subunit 3a antibody; eRF3a antibody; G1 to S phase transition protein 1 homolog antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P15170

Immunogen

Recombinant Human Eukaryotic peptide chain release factor GTP-binding subunit ERF3A protein (6-142AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200

Background

Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ERF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

GSPT1

Research Areas

Epigenetics and Nuclear Signaling