GRPR Antibody

Size

100ug

Clone Number

Aliases

BB2 antibody; Bombesin BB2 receptor antibody; bombesin receptor 2 antibody; Gastrin Releasing Peptide Receptor antibody; Gastrin-releasing peptide receptor antibody; GRP preferring bombesin receptor antibody; GRP R antibody; GRP-preferring bombesin receptor antibody; GRP-R antibody; Grp/bombesin receptor antibody; Grpr antibody; GRPR_HUMAN antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P30550

Immunogen

Recombinant Human Gastrin-releasing peptide receptor protein (326-384AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200

Background

Receptor for gastrin-releasing peptide (GRP) (PubMed:1655761). Signals via association with G proteins that activate a phosphatidylinositol-calcium second messenger system, resulting in Akt phosphorylation. Contributes to the regulation of food intake. Contributes to the perception of prurient stimuli and transmission of itch signals in the spinal cord that promote scratching behavior, but does not play a role in the perception of pain. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

GRPR

Research Areas

Neuroscience; Signal transduction