GRO beta Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine| which| in vitro| suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.|online information:CXCL2 entry|pharmaceutical:GRO-beta(5-73) is available under the name Garnocestim as immunomodulator. It is used prior to hematopoietic transplantation for peripheral blood stem cell mobilization and reduction of incidence| duration| and/or severity of chemotherapy induced cytopenias.|PTM:The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.|Belongs to the intercrine alpha (chemokine CxC) family.|

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human GROβ

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

11770

synonyms

GROβ; C-X-C motif chemokine 2; Growth-regulated protein beta; Gro-beta; Macrophage inflammatory protein 2-alpha; MIP2-alpha; GRO-beta;5-73; GRO-beta-T; Hematopoietic synergistic factor; HSF; SB-251353;