GRO alpha Polyclonal Antibody

Ab type

Primary antibody

Background

This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthetic peptide from human protein at AA range: 70-107

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

Growth-regulated alpha protein ;C-X-C motif chemokine 1;GRO-alpha;1-73;Melanoma growth stimulatory activity;MGSA;Neutrophil-activating protein 3;NAP-3 [Cleaved into: GRO-alpha;4-73; GRO-a; Growth-regulated alpha protein; C-X-C motif chemokine 1; GRO-alpha;1-73; Melanoma growth stimulatory activity; MGSA; Neutrophil-activating protein 3; NAP-3; GRO-alpha;4-73; GRO-alpha;5-73; GRO-alpha;6-73;