GRIK2 (GluR6) Polyclonal Antibody

Ab type

Primary antibody

Background

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthetic Peptide of GRIK2 (GluR6)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

Glutamate receptor, ionotropic kainate 2 ;Excitatory amino acid receptor 4;EAA4;Glutamate receptor 6;GluR-6;GluR6; Glutamate receptor, ionotropic kainate 2; Excitatory amino acid receptor 4; EAA4; Glutamate receptor 6; GluR-6; GluR6