GRB14 Polyclonal Antibody

Ab type

Primary antibody

Background

Growth factor receptor-bound protein 14 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. GRB14 encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Growth factor receptor-bound protein 14 likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. GRB14 may play a role in signaling pathways that regulate growth and metabolism. Alternative splicing results in multiple transcript variants.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human GRB14. AA range:81-130

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

60988

synonyms

GRB14; Growth factor receptor-bound protein 14; GRB14 adapter protein